In this article you will get to learn more about the condition known as Azoospermia,  Azoospermia drugs and treatment in Nigeria.

What is Azoospermia?

Azoospermia drugs

Photo credit: Welling Homeopathy

Azoospermia is a condition in which a man's ejaculate contains no detectable sperm (semen). Male infertility is caused by azoospermia.

Azoospermia is when a man's ejaculate contains no sperm (No sperm count). Here's a basic rundown of how the human body functions: The testicles are where sperm is produced. It passes through the female reproductive system and combines with the seminal duct fluid.

The sperm and this fluid combine to form semen, which is the thick, white ejaculate that emerges from the penis.

The sperm is removed from the equation in azoospermia. Ejaculate may exist, but it does not contain sperm. Although you may be acquainted with the phrase "low sperm count," azoospermia is referred to as "no sperm count."

Types of Azoospermia

There are three types:

  1. Pre-testicular azoospermia (non-obstructive) is caused by a decrease in the generation of sperm-producing hormones.
  2. Any abnormalities in the function or structure of the testicles induce testicular azoospermia (non-obstructive).
  3. Obstructive post-testicular azoospermia is caused by difficulty with ejaculation induced by a blockage in the reproductive system.

Azoospermia causes

Azoospermia may be caused by a number of factors, including genital obstruction, infection, genital injury, surgical effects on the male reproductive system, lifestyle choices, excessive drugs, alcohol intake, and illicit drug usage.

Men with azoospermia make up around 2% of the global population. Oligospermia is a more common condition. The low concentration of sperm cells in the sperm is referred to as oligospermia ( low sperm count). It affects roughly 15% of all males and about 40% of men who are being assessed for infertility.

How does azoospermia manifest itself?

You may not notice any signs or even realize you have azoospermia until your attempts to conceive fail. Any additional indications or symptoms you have might be due to the underlying reasons, such as hormone imbalances or hereditary chromosomal disorders.

Low sex drive erectile dysfunction bulge, swelling, or pain around the testicles reduced hair on the face or body are all potential signs.

Azoospermia drugs and treatment in Nigeria

Azoospermia drugsPhoto credit: inviTRA

Azoospermia may be treated in two ways: obstructive or non-obstructive. Fertility medicines that treat non-obstructive azoospermia include:

  • Clomiphene citrate (clomid)
  • Hormone that stimulates the formation of follicles (FSH)
  • hCG stands for human chorionic gonadotropin (HCG)
  • Bromocriptine
  • Anastrazole
  • Letrazole
  • Injections of testosterone

The etiology of azoospermia affects the treatment. Understanding and treating azoospermia typically requires genetic testing and counseling. Some treatment options include:

Surgery may unblock tubes or repair and join abnormal or never produced tubes if a blockage is the cause of your azoospermia.

Hormone therapy may be prescribed if poor hormone production is the primary reason. Follicle-stimulating hormone (FSH), human chorionic gonadotropin (HCG), clomiphene, anastrazole, and letrozole are examples of hormones.

If a varicocele is causing low sperm production, the affected veins may be cut up surgically while the surrounding tissues are intact.

In certain men, sperm may be extracted straight from the testicle by a thorough biopsy. If there are living sperm in the testes, epididymis, or vas deferens, they can be extracted for assisted pregnancy procedures like in vitro fertilization or intracytoplasmic sperm injection.

our healthcare professional may propose genetic testing of your sperm before considering assisted conception techniques if the cause of azoospermia is deemed to be something that can be passed down to offspring.

If there is an active infection, it should be treated first before moving on to other therapies. While some men may show signs of infection, up to one in four men will show no signs of infection. Even if they don't show any symptoms, the infection might disrupt their fertility and cause lasting harm to their reproductive system.

Surgical Reconstruction

Blockages and severed  connections may be restored with microsurgical therapy in certain instances of obstructive azoospermia. A varicocele may be removed or treated with surgery, and retrograde ejaculation can also be treated with surgery.

Natural conception may be feasible if obstructive azoospermia can be corrected with surgery. Surgical procedures, on the other hand, do not solve the issue overnight. Three to six months after surgery, a semen analysis will be ordered.

If sperm levels are normal and the female partner has no fertility issues, the couple may be able to conceive naturally. Other options can be considered if sperm levels are still abnormal after surgery.

Hormonal Support or Medication

Azolospermia can be treated with medication in some cases. Retrograde ejaculation, for example, can sometimes be treated with medications, allowing for natural conception.

In some azoospermic men, hormone therapy can help to stimulate sperm development.

Hormonal support can sometimes help sperm cells return to the sperm. In some cases, it will allow enough sperm development for healthy sperm cells to be extracted from the testicle via a testicular biopsy.

Is there anything natural that can help?

With azoospermia, home remedies for sperm production may or may not work. While a low sperm count may react well to specific herbs and dietary modifications, sperm that is missing owing to an obstruction or a hereditary problem may not (if at all).

That's not to suggest that eating a well-balanced diet, getting enough of rest, drinking lots of water, and managing stress can't help. Aside from looking after your overall health, consult with your doctor to see what natural therapies, if any, may be beneficial to you.

Things to attempt include:

To promote sperm production, eat a diet rich in complete, nutrient-dense meals.

Exercise every day. This may assist in increasing testosterone levels.

Reduce your stress levels by practicing yoga or meditation. The stress hormone cortisol may affect testosterone synthesis.

Ask your doctor about herbs and supplements like Tribulus terrestris, black seed, Coenzyme Q10, folic acid, horse chestnut, L-carnitine, Panax ginseng, and zinc, which may help with male fertility.

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